Today’s analytical challenges require tomorrow’s Quantitation solutions

The world of Quantitation is always changing. You use Quantitation to answer questions about the world we live in and every day those questions grow in complexity. Today’s analytical challenges are making Quantitation about more than just quantifying targeted analytes. As a result, there may come a time when you realize you need to screen and quantify untargeted analytes as well. It’s a different way of doing Quantitation that requires both a qualitative and a quantitative assessment. The current way of doing Quantitation doesn’t give you easy access to both with one workflow, but tomorrow’s Quantitation does. By adopting tomorrow’s Quantitation today, you’ll be able to provide better answers to new analytical challenges.


 
 

Tomorrow's Quantitation
ensures better food safety today

Tomorrow's Quantitation gives you the ability to screen and quantify targeted and untargeted analytes in food matrices with greater efficiency and productivity compared to what you have today. In the last decade, the number of pesticides used to ensure the safety of our food has grown significantly and the nature of pesticides and food matrices are becoming increasingly more complex. To address these challenges, analytical laboratories need to identify and quantify hundreds of pesticides across a broad range of food matrices. Tomorrow’s Quantitation gives you the workflows you need to provide better answers to more analytical challenges in food safety.

Dr. Günther Raffler on the future challenges of strong food safety regulations

The number of complex contaminants that can affect food safety has steadily increased, while regulations for detection limits get lower and lower. Dr. Raffler, Manager of Food Chemistry at Eurofins, discusses why the future of food safety will require the sensitivity of MS in combination with LC or GC.

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Dr. Stuart Adams on the changing expectations for pesticide analysis

The industry is moving towards requiring more information for less effort per sample. Senior Analytical Chemist at FERA Science Ltd, Dr. Stuart Adams, discusses the need for quantitative and qualitative information to come together, so that labs can efficiently report the correct results.

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Pesticide analysis in food and beverages application compendium

Powerful workflow solutions for ever-evolving pesticide residue analysis. This comprehensive compendium includes sample preparation techniques to simplify analysis and an extensive collection of application notes for LC-MS and other relevant technologies.

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Watch and learn



Utilizing the power of LC-Orbitrap MS Technology for the multi-residue analysis of pesticides

Łukasz Rajski, from the European Union Reference Laboratory, provides an independent evaluation of the capabilities of Thermo Scientific™ Orbitrap™ mass analyzer technology for pesticide analysis.

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Whiteboard video: Scientists are rethinking HRAM for food safety

Labs around the world are shifting from traditional workflows to high resolution for both qualification and quantitation. Find out why and how.

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Start-to-finish, comprehensive QQQ workflows for pesticide analysis

Address the challenges of pesticide analysis with increased sensitivity, speed and specificity in a comprehensive solution that comes fully stocked with methods you can use moments after setup is complete.

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HRAM publication collection

Orbitrap mass spectrometer technology is now used extensively for the quantitation of small and large molecule analytes in a broad range of clinical research, forensic toxicology, pharmaceutical discovery, environmental analysis and food testing applications. The result is a steadily-increasing collection of peer-reviewed publications highlighting the benefits of performing quantitative analysis with Orbitrap mass spectrometers.

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Challenges in pesticide quantitation

Regulations to identify and quantify pesticides are constantly changing to ensure increased food safety, making the screening and routine quantitation of pesticide residues an important and demanding application in food safety.

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Making the switch to HRAM for pesticides analysis

Dr. Susanne Ekroth discusses how LC-Orbitrap technology will help in the development of multi-residue pesticide methods at the Swedish National Food Agency.

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Instruments for tomorrow's Quantitation

As the world of Quantitation continues to evolve, we can help your laboratory address the challenges you face. From screening and confirmation of unknowns to detection and fast Quantitation of hundreds of known targets with high sensitivity - we have an outstanding array of analytical instruments and the comprehensive workflows you need to address tomorrow’s Quantitation challenges, today.

TSQ Quantiva Triple Quadrupole Mass Spectrometer

As the gold standard for targeted quantitation, the Thermo Scientific™ TSQ Quantiva™ Quadrupole Mass Spectrometer exceeds the most stringent analytical requirements for quantitative performance with attogram-level sensitivity, unprecedented usability and exceptional robustness. It ensures sensitive and reproducible quantitation for fragile samples used in clinical research and forensic toxicology. Method development is fast and simple, making it easy to keep up with the rapidly growing list of threats to the environment and food supply. It also provides the highly productive performance needed for pharmaceutical research.

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Q Exactive Focus Hybrid Quadrupole-Orbitrap Mass Spectrometer

The Thermo Scientific™ Q Exactive™ Focus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer brings the benefits of HRAM data to laboratories performing routine analyses ranging from targeted quantitation to non-targeted screening. HRAM MS allows you to detect and quantify all precursor ions in a sample without the need for individual compound tuning and optimization. With the Q Exactive Focus MS, you get highly selective detection and quantitation of both targeted and non-targeted compounds in complex matrices with minimal method development, saving time and increasing lab productivity.

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Vanquish Flex Binary UHPLC System

The Thermo Scientific™ Vanquish™ Flex Binary UHPLC System is an ultra-high performance liquid chromatography system designed for accuracy, precision and sensitivity. It can accurately handle thousands of samples with excellent injections. With industry-leading flow and gradient precision, it drives the separation with more power. In addition, even-temperature control allows you to control the separation with more confidence and its excellent signal-to-noise ratio allows you to detect the analyte with more sensitivity.

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Resources to start exploring
the future of Quantitation

The following resources draw on the expertise of experienced scientists to provide unique perspectives on the future of Quantitation and the instruments and workflows that will define it.
 

Affordable, high resolution LC-MS/MS has arrived

The Q Exactive Focus Mass Spectrometer helps analytical labs overcome challenges and achieve research goals.

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Live demonstration of pesticide analysis solutions

A previously recorded, live demonstration of start-to-finish workflow solutions for pesticide analysis.

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Pesticide residue analysis

On-demand webinar detailing the development and implementation of complete, validated and ready-to-go LCMS workflow solutions leveraging both HRAM and triple quadrupole MS technology.

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Fully tested LC-MS workflow for pesticide residues

Comprehensive LC-MS solution for quantitation of more than 250 pesticides below maximum residue limits and within stringent EU guidelines.

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Increased productivity in pesticide residue analysis

Simultaneous, high-throughput quantitative analysis of 440 pesticide residues in bell pepper obtained with a triple quadrupole MS.

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Quantitative and qualitative analysis using HRAM

A method for pesticide residue analysis using a full-scan, data-dependent MS/MS workflow and the HRAM spectral library for identification and confirmation.

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The analysis of polar pesticides by ion-exchange chromatography tandem mass spectrometry

Dr. Stuart Adams, FERA Science Ltd, provides an analysis of polar pesticides, the QuPPE method and the IC-MS/MS instruments and software used for analysis.

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EPRW 2016 feature poster presentation: pesticide residue analysis

Poster discussing pesticide analysis using full scan high resolution MS presented at the 11th European Pesticide Residue Workshop (EPRW).

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EPRW 2016 feature poster presentation: polar ionic pesticides

Poster discussing IC-MS/MS polar ionic pesticide analysis presented at the 11th European Pesticide Residue Workshop (EPRW).

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Being on the safe side: pesticide quantitation with a comprehensive LC-MS workflow

Learn about the development and implementation of validated workflow solutions with LC-MS/MS for routine quantitation and screening of pesticide residues in food products.

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